Our readers keep the lights on and my morning glass full of iced black tea. As an Amazon Associate, I earn from qualifying purchases.7 Best Shake For Muscle Gain | 700 Calories Per Scoop or Overkill

Hitting a daily calorie surplus is the single biggest challenge for hardgainers and athletes trying to pack on lean mass. Liquid calories from a shake bypass appetite fatigue and deliver dense nutrition fast, but the market is flooded with options that are either low on protein, loaded with filler sugars, or simply too thin to keep you full. The right formula balances total energy, protein quality, digestibility, and micronutrient density.

I’m Mohammad — the founder and writer behind ProteinJug. I’ve spent years analyzing protein powder formulations, third-party lab tests, and user-reported digestive outcomes to separate high-quality muscle gainers from glorified sugar water.

After cross-referencing label claims, ingredient sourcing, and hundreds of verified reviews, I’ve compiled the definitive list of the best shake for muscle gain to save you time and stomach space.

How To Choose The Best Shake For Muscle Gain

A mass gainer is only as good as its macronutrient split. The wrong ratio can leave you feeling bloated and storing fat instead of building lean tissue. Focus on these three factors before you buy.

Calorie Density Per Serving

Look for at least 500 calories per serving. A shake that delivers 750 to 1250 calories is ideal for hardgainers who struggle to eat enough solid food. Lower-calorie protein powders are for maintenance or cutting, not for serious mass gain.

Protein Source and Digestibility

Whey protein isolate is fast-absorbing and rich in BCAAs, making it the gold standard for post-workout recovery. Beef protein isolate is an excellent lactose-free alternative that digests easily and delivers a high concentration of amino acids per gram. Avoid gainers that rely heavily on collagen or gelatin to pad their protein numbers.

Carbohydrate Quality and Sugar Content

High-quality mass gainers use complex carbohydrates like maltodextrin or oat flour to provide sustained energy. Formulas with less than 10 grams of sugar per serving are preferable to avoid insulin spikes and fat gain. Watch for gainers that list sugar or corn syrup solids as first or second ingredients.

Quick Comparison

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Model Category Best For Key Spec Amazon
Boost Very High Calorie (24-pack) Ready-to-Drink Medical weight gain 530 cal / 22g protein Amazon
Optimum Nutrition Gold Standard Whey Whey Powder Lean muscle & cutting 24g protein / 1g sugar Amazon
MuscleMeds Carnivor Mass (6lb) Beef Mass Gainer Lactose-free mass gain 50g protein / 0g fat Amazon
Boost Very High Calorie (12-pack) Ready-to-Drink Appetite recovery 530 cal / 26 vitamins Amazon
Optimum Nutrition Gold Standard Pro Gainer Whey Mass Gainer High-calorie bulk 650 cal / 60g protein Amazon
GNC AMP Mass XXX Clinical Mass Gainer Strength & stamina 780 cal / creatine + betaine Amazon
MuscleMeds Carnivor Mass Big Steer 1250 Extreme Mass Gainer Maximum calories per shake 1250 cal / 255g carbs Amazon

In‑Depth Reviews

Calorie Heavyweight

1. Boost Very High Calorie Nutritional Drink (24-pack)

Ready-to-Drink530 Calories

This ready-to-drink shake delivers 530 calories and 22 grams of protein per 8-ounce serving, along with 26 vitamins and minerals. The variety pack includes Vanilla, Chocolate, and Strawberry — giving you flavor rotation to combat palate fatigue during daily use. The consistency is notably thicker than standard nutritional shakes, which helps with satiety but can be tough for some to drink quickly.

Real-world feedback from caregivers and individuals managing medical weight loss highlight its effectiveness: users report steady weight maintenance and even gains when using it as a mini-meal replacement. The chocolate flavor earned high marks for taste, while the vanilla was described as reminiscent of melted ice cream. Several reviewers noted that drinking it chilled or over ice reduces the thickness and improves drinkability.

At 530 calories per bottle, this is an excellent choice for anyone who needs a dense, nutrient-packed shake without mixing or measuring. The lactose content may cause mild bloating for sensitive individuals, but the convenience and complete nutritional profile make it a strong daily option for both recovery and weight gain.

Why it’s great

  • Perfect for low appetite — 530 cal in small volume
  • Includes 26 vitamins and minerals for immune and bone support
  • Great taste feedback across all three flavors

Good to know

  • Thick consistency can be off-putting for some users
  • Higher sugar content than powder-based gainers
Lean Mass Choice

2. Optimum Nutrition Gold Standard 100% Whey Protein Powder

Whey Isolate24g Protein

With 24 grams of whey protein — primarily from isolate — and just 1 gram of sugar per serving, this is the benchmark for clean, fast-absorbing protein. It delivers 5.5 grams of naturally occurring BCAAs per scoop, making it a top-tier option for post-workout muscle repair. The Double Rich Chocolate flavor is widely praised for being smooth, not overly sweet, and mixing effortlessly in water or milk without clumps.

Long-term users consistently highlight its reliable digestive tolerance and consistent mixing quality across multiple tubs. The instantized formula dissolves with a spoon in about 20-30 seconds of shaking, which is ideal for quick post-gym nutrition. At its core, this is a whey concentrate/isolate blend that prioritizes purity over calorie density — you get protein without the excess fat or carbs.

This shake is best suited for athletes who already eat enough calories from whole foods and need a clean protein boost to support lean muscle. It isn’t a mass gainer, so pairing it with milk, oats, or peanut butter creates a more calorie-dense shake. A small subset of users reported mild allergic reactions, so those with dairy sensitivities should sample cautiously.

Why it’s great

  • Exceptional mixability — no clumps or grit
  • Low sugar and fat ideal for lean bulking
  • Trusted brand with 35 years of consistent quality

Good to know

  • Not a high-calorie mass gainer on its own
  • Minor allergic reactions reported by some users
Lactose-Free Winner

3. MuscleMeds CARNIVOR Mass Gainer Beef Protein Isolate

Beef Isolate50g Protein

This mass gainer is built around hydrolyzed beef protein isolate — a lactose-free, fat-free protein source that is 350% more concentrated in amino acids than steak. Each serving packs 50 grams of protein, 125 grams of carbohydrates, and over 700 calories, with zero fat and zero sugar. The Chocolate Peanut Butter flavor is surprisingly palatable for a beef-based product, mixing easily without the thick, pudding-like consistency common in many mass gainers.

User feedback consistently praises its filling nature and ability to stave off hunger for hours — one reviewer noted it replaced dinner without triggering hunger until the next morning. The fast-digesting beef isolate is designed to spike blood amino acids rapidly, which supports faster muscle protein synthesis and glycogen replenishment. It is also Halal certified, broadening its appeal for those with dietary restrictions.

The main trade-off is the faint beef smell that some users detect, especially when mixing with water. Using a blender with almond milk or oat milk can mask the aroma and improve texture. Overall, this is an outstanding option for anyone who cannot tolerate whey but still wants a high-calorie, high-protein mass gainer.

Why it’s great

  • Zero lactose or dairy — ideal for sensitive stomachs
  • 50g protein with zero fat and zero sugar
  • Halal certified and uses real beef isolate

Good to know

  • Faint beef smell may require flavor masking
  • High carb load may cause bloat in some users
Best Value Drink

4. Boost Very High Calorie Nutritional Drink (12-pack)

Ready-to-Drink530 Calories

This is the same 530-calorie formula as the variety pack, but offered in a single-flavor 12-pack of Chocolate. With 22 grams of protein, 26 vitamins, and a richer mouthfeel, it functions as a convenient mini-meal for those with suppressed appetites. The smaller pack size makes it a good entry point for testing tolerance before committing to the larger 24-count.

Multiple reviews from caregivers for cancer patients and elderly relatives emphasize its role in halting weight loss. The thickness is again a recurring point — while it provides calorie density, some users with swallowing difficulties found it too heavy. Chilling the bottle or mixing over ice significantly improves drinkability without diluting the caloric value.

This is a practical, no-prep option for medical weight gain or for hardgainers who want a grab-and-go shake during busy days. It is not designed for extreme muscle-building macros (higher protein would be ideal), but its complete micronutrient profile makes it a better choice than generic supermarket meal replacements.

Why it’s great

  • No mixing or cleanup — shake and drink
  • Excellent for patients or people with low appetite
  • Complete vitamin profile supports overall health

Good to know

  • Thicker consistency not for everyone
  • Only 22g protein per 530 calories
Creamy Bulker

5. Optimum Nutrition Gold Standard Pro Gainer

Whey Blend650 Calories

This mass gainer delivers 650 calories, 60 grams of protein, and more than 80 grams of carbohydrates per serving, with less than 8 grams of sugar. The Vanilla Custard flavor is a standout — users describe it as rich, creamy, and free of the artificial aftertaste that plagues many vanilla protein powders. The formula uses a blend of whey protein isolate, concentrate, and calcium caseinate for both fast and slow-digesting protein.

Some users reported gaining 5 pounds within the first week of using one shake daily alongside regular training. The mixability is excellent for a mass gainer; it dissolves smoothly in a shaker without excessive clumping. However, the serving size yields only 14 scoops per container (despite the tub suggesting 28), so the cost per serving is higher than expected.

This is a strong pick for athletes who want a calorie-dense whey-based shake without the excess sugar common in budget gainers. The protein blend supports both immediate recovery and sustained overnight muscle repair, making it versatile for morning or post-workout use. Pair it with whole milk for an even bigger calorie boost.

Why it’s great

  • Vanilla Custard flavor is exceptionally creamy
  • Dual-release protein blend for extended recovery
  • Low sugar per calorie count

Good to know

  • Fewer servings per tub than packaging suggests
  • Contains dairy — not suitable for lactose intolerance
Strength Scientist

6. GNC AMP Mass XXX

Clinical Formula780 Calories

Mass XXX packs 780 calories, 50 grams of protein, and an evidence-backed blend of MyoTOR (a patented amino acid metabolite), creatine, and BETAPOWER betaine. Clinical testing claims it can improve strength with 40% fewer sets and accelerate muscle endurance within two weeks. The Vanilla flavor receives positive marks for taste, and the 6-pound tub provides 13 servings.

This is one of the few mass gainers on the market that goes beyond basic macros and includes ergogenic aids explicitly studied for resistance training performance. Creatine monohydrate is well-documented for strength gains, and betaine has emerging data supporting improved power output. Users who reviewed it after regular gym use reported noticeable improvements in workout volume and recovery.

The cost per serving is higher than standard gainers, and the proprietary blend makes it harder to know exact doses of individual ingredients. It is best suited for intermediate to advanced lifters who want a performance-oriented gainer rather than just calories. Those sensitive to creatine should assess their tolerance before committing to a full tub.

Why it’s great

  • Includes creatine and betaine for performance
  • Clinically tested MyoTOR compound for strength
  • WADA banned-substance tested for competition

Good to know

  • Only 13 servings per container
  • Proprietary blends limit ingredient transparency
Extreme Density

7. MuscleMeds Carnivor Mass Big Steer 1250

Beef Isolate1250 Calories

This is one of the most calorie-dense mass gainers available — 1,250 calories per serving from hydrolyzed beef protein isolate and 255 grams of carbohydrates, with zero sugar and zero fat. Each serving also contains 50 grams of clinically tested beef protein, plus chromium and 4-hydroxyisoleucine for insulin and carb control. The massive 15-pound tub is built for heavy daily consumption.

User feedback from those with severe lactose intolerance highlights how easy this is on the digestive system compared to whey-based gainers. The chocolate flavor is described as decent, though the powder requires a blender or oversized shaker with at least 24 ounces of water to avoid clumping. Some users noted an artificial aftertaste, but most agreed it is palatable for the calorie density.

This is a niche product aimed at extreme hardgainers and athletes who need the highest possible calorie intake in the smallest liquid volume. The sugar-free carbohydrate profile is a major plus for those who want to avoid insulin spikes. Storage of the large container and the higher cost per tub are the main practical downsides to consider before buying.

Why it’s great

  • 1250 calories with zero sugar or fat
  • Lactose-free beef isolate ideal for dairy intolerance
  • Insulin-controlling ingredients reduce fat storage risk

Good to know

  • Requires blender or large shaker to mix properly
  • Massive 15 lb tub is awkward to store

FAQ

Can I use a whey protein shake instead of a mass gainer to build muscle?
Standard whey shakes provide around 100-200 calories per serving. For muscle gain, you need a consistent daily surplus of 300-500 calories. Mass gainers pre-blend protein and carbs to hit 500-1250 calories per shake, making it easier to reach that surplus without forcing down extra meals or adding ingredients to plain whey.
Are mass gainers with high sugar content bad for muscle gain?
Not necessarily harmful, but they can promote fat gain. High-sugar formulas spike insulin and may lead to storing more calories as fat instead of muscle. Look for gainers with less than 10 grams of sugar and carbohydrate sources like maltodextrin or oat flour for sustained energy without excessive sweetness.
How many times a day should I drink a shake for muscle gain to see results?
One shake per day is typically enough to support a caloric surplus when combined with solid meals. Drinking two shakes daily can accelerate weight gain, but it increases the risk of replacing whole food calories. Start with one shake post-workout or as a breakfast supplement and adjust based on weekly weight changes.

Final Thoughts: The Verdict

For most users, the best shake for muscle gain winner is the MuscleMeds Carnivor Mass (6lb) because it delivers 50 grams of clean beef protein and 700 calories without any lactose or sugar. If you want a convenient ready-to-drink option for medical or low-appetite weight gain, grab the Boost Very High Calorie (24-pack). And for extreme hardgainers needing maximum calories per shake, nothing beats the MuscleMeds Carnivor Mass Big Steer 1250.

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